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PostDoctoral Associate

Requisition Number:



Boulder, Colorado

Employment Type:

Research Faculty



Date Posted:


Job Summary

The Department of Biochemistry seeks applications for a full-time PostDoctoral Associate to work in the laboratory of Professor Natalie Ahn.

The primary purpose of the position is to investigate mechanisms of signal transduction involved in the regulation of protein kinases and cancer. The specific goals are to investigate enzymatic mechanisms for the regulation of MAP kinases, their impact on inhibitor design, and their contribution to drug resistance in cancer. Projects include : analysis of signaling mechanisms by functional proteomics, phosphoproteomics, hydrogen-deuterium exchange mass spectrometry, and NMR. Relevant publications include: Kavran et al. 2022 PNAS 119:e2113535119; Pegram et al, 2019 PNAS 116:15463; Xiao et al., 2014 PNAS 111:2506.

The University of Colorado Boulder is committed to building a culturally diverse community of faculty, staff, and students dedicated to contributing to an inclusive campus environment. We are an Equal Opportunity employer, including veterans and individuals with disabilities.

Who We Are

The Department of Biochemistry at the University of Colorado Boulder is world-renowned for research and teaching in molecular biosciences and biomedicine. This laboratory is located in the beautiful Rocky Mountain city of Boulder, CO, and housed in the state-of-the-art Jennie Smoly Caruthers Biotechnology building on East Campus.

What Your Key Responsibilities Will Be

Experimental Design, Data Collection, and Analysis
  • Research-level experimental design in biochemistry, biophysics, and cancer biology.
  • Analysis of protein conformational dynamics and inhibitor binding by hydrogen-exchange mass spectrometry and 2D-NMR, and/or analysis of cellular responses to protein kinase inhibitors and anticancer drugs using biochemical assays, quantitative proteomics, phosphoproteomics, transcriptome sequencing, and mammalian cell light microscopy.
  • Protein expression, purification, and biophysical characterization.
  • Quantitative data analysis, computational methods' development.
  • Scientific writing and manuscript preparation.
  • Collaborative interactions with research team members.

Lab Management

  • Supervision of student trainees.
  • Ordering of supplies and equipment.
  • Maintenance of laboratory instrumentation.

What You Should Know

  • This position will function in a 40-hour work week Monday through Friday, with occasional time-sensitive research tasks needed on weekends.
  • All University of Colorado Boulder employees are required to align with the campus COVID-19 vaccine requirement. New employees must provide proof of vaccination or receive a medical or religious exemption within 30 days of employment.

What We Can Offer

The salary range for this full-time position is $53,000- $70,000.


The University of Colorado offers excellent benefits, including medical, dental, retirement, paid time off, tuition benefit and ECO Pass. The University of Colorado Boulder is one of the largest employers in Boulder County and offers an inspiring higher education environment. Learn more about the University of Colorado Boulder.

Be Statements

Be ambitious. Be groundbreaking. Be Boulder.

What We Require

  • A Ph.D. from an accredited institution in biochemistry, biology or related fields.

What You Will Need

  • Strong proficiency with independent research, including experimental design and execution, quantitative analysis and data interpretation, literature review, and critical thinking.
  • Good communication and teaching skills.
  • Scientific writing skills.

What We Would Like You To Have

  • Prior experience with mass spectrometry, NMR, protein purification, and/or cancer biology.
  • A commitment of two or more years.

Special Instructions

To apply, please submit the following materials:
  1. Resume or CV including name and contact information for three references.
  2. Cover letter addressed to the Search Committee briefly describing your qualifications, professional goals, and specific interest in this position.
  3. Optional: Transcripts/Proof of Degree
If you are selected as the finalist, your degree will be verified by the CU Boulder Campus Human Resources department using an approved online vendor. If your degree was obtained outside of the United States, please submit a translated version as an optional attachment.

During the application process you will need to enter contact information for a reference. We will request a letter of recommendation and additional materials, if needed, as the search progresses. 

Review of applications will begin immediately and remain open until filled.

Note: Application materials will not be accepted via email. For consideration, applications must be submitted through CU Boulder Jobs.

Posting Contact Information

Posting Contact Name: Natalie Ahn

Posting Contact Email: